Health Now
Live

Depression (mood)

Depression is a mental state of low mood and aversion to activity. It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. Depression affects a person's thoughts, behavior, feelings, and sense of well-being. The pleasure or joy that a person gets from certain experiences is reduced, and the afflicted person often experiences a loss of motivation or interest in those activities. People with depression may experience sadness, feelings of dejection or lack of hope, difficulty in thinking and concentration, hypersomnia or insomnia, overeating or anorexia, or suicidal thoughts.

Read more on Wikipedia →

1,440trials recruiting now
United Statesmost trial sites (628)
400+mapped site locations
Massachusetts General most active sponsor

Trials by phase

  • Early phase 112
  • Phase 148
  • Phase 2149
  • Phase 361
  • Phase 443
  • Not applicable (device/behavioral)937
  • Observational study223

Phase 1 tests safety, phase 2 tests whether it works, phase 3 compares it with standard care, phase 4 follows it after approval.

Countries with the most trials

  • United States628
  • Canada118
  • China111
  • France77
  • Spain47
  • Turkey (Türkiye)45
  • United Kingdom45
  • Taiwan43

Where trials are recruiting

Each dot is a site city; bigger dots have more recruiting trials. Showing up to 400 locations.

Lead sponsors

Massachusetts General Hospital · 25Weill Medical College of Cornell University · 18Medical University of South Carolina · 17University of Pittsburgh · 15Centre for Addiction and Mental Health · 14Assistance Publique - Hôpitaux de Paris · 13VA Office of Research and Development · 13Mclean Hospital · 12

Newest recruiting trials

See all 1,440 on ClinicalTrials.gov →

General information only, not medical advice. Trial listings are written by sponsors; eligibility and contacts are on each official listing.