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Hypertension
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide.
1,207trials recruiting now
United Statesmost trial sites (424)
400+mapped site locations
Mayo Clinicmost active sponsor
Trials by phase
Phase 1 tests safety, phase 2 tests whether it works, phase 3 compares it with standard care, phase 4 follows it after approval.
Countries with the most trials
Where trials are recruiting
Each dot is a site city; bigger dots have more recruiting trials. Showing up to 400 locations.
Lead sponsors
Mayo Clinic · 15Vanderbilt University Medical Center · 15University of Alabama at Birmingham · 13Duke University · 13Assistance Publique - Hôpitaux de Paris · 13Johns Hopkins University · 9China National Center for Cardiovascular Diseases · 8University of California, San Francisco · 8
Newest recruiting trials
- Phase 2
Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
- Phase 1
Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
- Not applicable (device/behavioral)
Effect of Late Ripcord Removal From Glaucoma Drainage Device
- Not applicable (device/behavioral)
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy
- Not applicable (device/behavioral)
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
- Phase 2
Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans
- Not applicable (device/behavioral)
Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot Trial
- Phase 4
Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)
- Phase 2
Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
- Observational study
The Value of Spleen Thickness and Spleen Diameter for Gastroesophageal Varices Diagnosis in Compensated Cirrhosis
- Not applicable (device/behavioral)
Low Pneumoperitoneum Pressure for Delirium Prevention in Elderly Laparoscopy
- Phase 4
Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound
- Phase 2, Phase 3
The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension
- Observational study
Oxford Luteal Dysfunction and Placental Insufficiency Study
- Phase 2
A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.
- Phase 1, Phase 2
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
- Observational study
Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism
- Observational study
Pulmonary Hypertension (PH) Biorepository for Translational Research
- Not applicable (device/behavioral)
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
- Observational study
A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates
- Not applicable (device/behavioral)
Vagal Stimulation Therapy and Preeclampsia
- Not applicable (device/behavioral)
Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension
- Not applicable (device/behavioral)
Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
- Phase 4
A Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) in India (MK-7962-037)
- Phase 1, Phase 2
A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage
See all 1,207 on ClinicalTrials.gov →
General information only, not medical advice. Trial listings are written by sponsors; eligibility and contacts are on each official listing.