Lung cancer
Lung cancer is a malignant tumor that originates in the tissues of the lungs. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize, spreading to other parts of the body.
Breakdowns below use the 2,000 most relevant recruiting trials.
Trials by phase
Phase 1 tests safety, phase 2 tests whether it works, phase 3 compares it with standard care, phase 4 follows it after approval.
Countries with the most trials
Where trials are recruiting
Each dot is a site city; bigger dots have more recruiting trials. Showing up to 400 locations.
Lead sponsors
Newest recruiting trials
- Phase 3
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
- Not applicable (device/behavioral)
Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease
- Phase 1
DK222 Study at Hopkins
- Phase 2
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
- Phase 1, Phase 2
Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer
- Phase 2
A Study Evaluating The Combination of Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer
- Not applicable (device/behavioral)
A Restorative Justice-Based Lung Cancer Screening Decision-Making Support Intervention Tailored for Black Individuals to Increase Lung Cancer Screening Among Black Community Members, RESTORE Trial
- Phase 2
Befotertinib Plus Chemotherapy With an MRD-guided Adaptive Strategy for Treatment Escalation and Response Optimization in EGFR-mutated NSCLC Patients
- Observational study
Prospective Multiomic Analysis in Small-Cell Lung Cancer
- Not applicable (device/behavioral)
Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
- Phase 1, Phase 2
Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma
- Observational study
Predicting Response to Anti-PD-1/PD-L1 Immunotherapy by Plasma Extracellular Vesicle Analysis
- Phase 1
A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors
- Phase 2
Universal Immunization to Fortify Immunotherapy Efficacy and Response
- Phase 2
Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features
- Phase 3
Primary Radiotherapy In MEtastatic Lung Cancer
- Phase 1
A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.
- Phase 3
A Study Comparing QLC5508 in Combination With QL2107 Versus Tislelizumab Plus Platinum-based Chemotherapy in Participants Wih Treatment-naรฏve Extensive-Stage Small Cell Lung Cancer
- Phase 1
Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib
- Phase 1, Phase 2
Phase 1/2, Open-label Study of ETX-929, a KRAS Inhibitor in Participants With Advanced Solid Tumors
- Phase 1, Phase 2
CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
- Phase 1, Phase 2
XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors
- Observational study
Real-World Outcomes of Sevabertinib in HER2-Mutant Advanced NSCLC: A Bidirectional Cohort Study
- Phase 1
Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
- Phase 1, Phase 2
A Study of Dato-DXd in Participants With Solid Tumors [TROPION-PanTumor04 (TP04)]
See all 2,320 on ClinicalTrials.gov โ