Obesity
Obesity is a medical condition, considered a disease by multiple organizations, in which excess body fat has accumulated to such an extent that it can have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower BMI thresholds to define obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis.
Trials by phase
Phase 1 tests safety, phase 2 tests whether it works, phase 3 compares it with standard care, phase 4 follows it after approval.
Countries with the most trials
Where trials are recruiting
Each dot is a site city; bigger dots have more recruiting trials. Showing up to 400 locations.
Lead sponsors
Newest recruiting trials
- Phase 3
Weight Gain Prevention in Adolescents and Young Adults
- Observational study
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
- Not applicable (device/behavioral)
Stanford Healthy Goals Study
- Not applicable (device/behavioral)
Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
- Not applicable (device/behavioral)
The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary Syndrome
- Phase 1
Comparing the Extent to Which Maridebart Cafraglutide is Made Available in the Body of Participants Living With Overweight or Obesity After Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA)
- Not applicable (device/behavioral)
Whole-Body Vibration Training in Women With Obesity With and Without Type 2 Diabetes
- Not applicable (device/behavioral)
Lactobacillus Acidophilus and Inulin for Cognitive Impairment in Obesity
- Not applicable (device/behavioral)
An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being
- Observational study
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
- Phase 4
Mechanisms of Weight Loss: Tirzepatide vs Semaglutide
- Not applicable (device/behavioral)
OBEDIAM: Therapeutic Patient Education in Adults Living With Obesity, Diabetes, and Metabolic Disorders
- Phase 2
Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity
- Phase 3
A Study to Learn About the Study Medicine Called PF-08653944 Taken Once-Monthly Compared to Placebo in Chinese Adults With Overweight or Obesity
- Not applicable (device/behavioral)
SHIFT-TB: Nutrition Intervention and Evaluation
- Phase 3
Trial to Evaluate ALN-CIDEB in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
- Phase 3
Safety and Analgesic Efficacy of the Biased μ-Opioid Receptor Agonist Tegileridine for Post-Operative Analgesia in Patients Undergoing Bariatric Surgery
- Phase 3
Vibegron for ENergy Thinking and Resilience in Aging
- Not applicable (device/behavioral)
Preserving Muscle Mass During Incretin-Induced Weight Loss
- Phase 3
A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
- Phase 3
A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)
- Not applicable (device/behavioral)
Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication
- Observational study
Frontal EEG Dynamics During Anesthesia in Patients With Obesity and Normal Weight
- Phase 4
Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss
- Phase 1, Phase 2
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
See all 1,477 on ClinicalTrials.gov →