Type 2 diabetes
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. Other symptoms include increased hunger, having a sensation of pins and needles, and sores (wounds) that heal slowly. Symptoms often develop slowly. Long-term complications from high blood sugar include heart disease; stroke; diabetic retinopathy, which can result in blindness; kidney failure; and poor blood flow in the lower limbs, which may lead to amputations. A sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon.
Trials by phase
Phase 1 tests safety, phase 2 tests whether it works, phase 3 compares it with standard care, phase 4 follows it after approval.
Countries with the most trials
Where trials are recruiting
Each dot is a site city; bigger dots have more recruiting trials. Showing up to 400 locations.
Lead sponsors
Newest recruiting trials
- Not applicable (device/behavioral)
Whole-Body Vibration Training in Women With Obesity With and Without Type 2 Diabetes
- Phase 4
QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy
- Not applicable (device/behavioral)
Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
- Not applicable (device/behavioral)
Continuous Glucose Monitoring Systems in People With Type 2 Diabetes Not Treated With Insulin
- Not applicable (device/behavioral)
OBEDIAM: Therapeutic Patient Education in Adults Living With Obesity, Diabetes, and Metabolic Disorders
- Phase 2
A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes
- Not applicable (device/behavioral)
LIfestyle MEtabotype Study B (LIME-B)
- Phase 3
A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
- Not applicable (device/behavioral)
Ultrasound-Guided Thoracolumbar Fascia Injection for Chronic Low Back Pain in Patients With Type 2 Diabetes
- Phase 1
A Research Study to Check the Safety of NNC9836-0001 When Given to Healthy Participants and Participants With Type 2 Diabetes
- Observational study
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery
- Not applicable (device/behavioral)
Effects of a Specialized Diabetes and Heart Clinic and Detection of Unrecognized Heart Failure in People With Type 2 Diabetes and Cardiovascular Disease
- Not applicable (device/behavioral)
Neuromodulation for Metabolic Dysfunction
- Phase 3
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
- Phase 3
A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes
- Phase 3
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight
- Phase 4
A Research Study Looking at Kidney and Heart Health in Adults With Type 2 Diabetes and Chronic Kidney Disease Treated With Semaglutide in China
- Early phase 1
SMART 2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults With Type 2 Diabetes
- Observational study
LIfestyle MEtabotype Study A
- Phase 3
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
- Phase 1
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide Medication
- Observational study
Multimodal Glucose Prediction in Type 2 Diabetes
- Not applicable (device/behavioral)
Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes
- Phase 2
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
- Phase 1
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide Medication
See all 886 on ClinicalTrials.gov →